A NOVEL APPROACH TO TREAT WOUND BY ULTRAVIOLET C RADIATION

BOOTH NO : G6


Category : Health, Wellness & Wellbeing

ABSTRACT
Ultraviolet-C has been widely used for disinfection purposes due to its germicidal spectrum. The efficiencies of UVC-LED for P. A and S.A disinfections were investigated at the distances of 1, 1.5, and 2 cm for 30 and 60s. Bacterial inhibition zones were measured, followed by a morphological analysis under SEM. The viabilities of skin cells were further evaluated with the adoption of aforesaid exposure parameters. The inhibition zones were increased with the increment of exposure distances and duration. The highest records of 5.40±0.11 cm S.A inhibition were observed at the distance of 2 cm and 60s. Bacterial debris formation were visualized following the UVC-LED exposures. The cell viability were in a range of 75.20-99.00% and 82.00-100.00% for 30 and 60s exposures, respectively. Thus, UVC-LED with 275-nm wavelength is capable in providing bacterial disinfection while maintaining accountable cell viability which is suitable to be adopted in wound treatment.
BACKGROUND
The severity level of wound when it is changed can lead to dangerous infection caused by accumulation of bacterial colonies. The bacteria generally involved in wound infections are S.A, E. faecalis, P.A, anaerobic bacteria, coagulase-negative staphylococci like S.E with frequency of 93.5%, 71.1%, 52.2%, 39.1% and 45.7% respectively. The UV-C radiation has not been explored as a disinfection tool for wound for direct exposure. Therefore, the aim of this research was to assess the effects of UVC-LED at different exposure distances (1, 1.5, and 2 cm) for the duration of 30 and 60s on bacterial colony without the usage of chemical or any antibacterial agent. UV-C is considered hazardous to skin cells, therefore, UVC-LED was also exposed to the human skin fibroblast cells to clarify whether the UVC- LED would affect the human skin following disinfection on wound.
NEEDS
TO MINIMIZE THE CHEMICAL INTERACTION WITH SKIN
APPROACH
AN APPROACH TO TREAT AND DISINFECT WOUND WITHOUT THE USAGE OF CHEMICALS IN LESS TIME.
BENEFITS
CHEMICAL FREE WOUND DISINFECTION TECHNIQUE, LOW COST, LESS TIME CONSUMING
COMPETITORS
THERE ARE NO STUDIES ABOUT DISINFECTION TECHNIQUE AVAILABLE FOR DIRECT EXPOSURE TO SKIN FOR THE PURPOSE OF TREATMENT BY USING UV-C RADIATION.
POTENTIAL MARKET
LOCAL HOSPITALS, CLINICS, HOME
RESEARCH TEAM
TAN TIAN SWEE FAKULTI KEJURUTERAAN ELEKTRIK
JAHANZEB SHEIKH BIOMEDICAL ENGINEERING AND HEALTH SCIENCES JAHANZEB SHEIKH ELECTRICAL ENGINEERING LEONG KAH MENG BIOMEDICAL ENGINEERING AND HEALTH SCIENCES LEONG KAH MENG BIOSCIENCES AND MEDICAL ENGINEERING LEONG KAH MENG ELECTRICAL ENGINEERING MATTHIAS TIONG FOH THYE BIOMEDICAL ENGINEERING AND HEALTH SCIENCES MATTHIAS TIONG FOH THYE ELECTRICAL ENGINEERING SAMEEN AHMED MALIK UNIVERSITY OF ENGINEERING & TECHNOLOGY LAHORE TAN TIAN SWEE FAKULTI KEJURUTERAAN ELEKTRIK